2 results
Coronavirus disease 2019 is associated with long-term depressive symptoms in Spanish older adults with overweight/obesity and metabolic syndrome
- Sangeetha Shyam, Carlos Gómez-Martínez, Indira Paz-Graniel, José J. Gaforio, Miguel Ángel Martínez-González, Dolores Corella, Montserrat Fitó, J. Alfredo Martínez, Ángel M. Alonso-Gómez, Julia Wärnberg, Jesús Vioque, Dora Romaguera, José López-Miranda, Ramon Estruch, Francisco J. Tinahones, José Manuel Santos-Lozano, J. Luís Serra-Majem, Aurora Bueno-Cavanillas, Josep A. Tur, Vicente Martín Sánchez, Xavier Pintó, María Ortiz Ramos, Josep Vidal, Maria Mar Alcarria, Lidia Daimiel, Emilio Ros, Fernando Fernandez-Aranda, Stephanie K. Nishi, Oscar García Regata, Estefania Toledo, Jose V. Sorli, Olga Castañer, Antonio Garcia-Rios, Rafael Valls-Enguix, Napoleon Perez-Farinos, M. Angeles Zulet, Elena Rayó-Gago, Rosa Casas, Mario Rivera-Izquierdo, Lucas Tojal-Sierra, Miguel Damas-Fuentes, Pilar Buil-Cosiales, Rebeca Fernández-Carrion, Albert Goday, Patricia J. Peña-Orihuela, Laura Compañ-Gabucio, Javier Diez-Espino, Susanna Tello, Ana González-Pinto, Víctor de la O, Miguel Delgado-Rodríguez, Nancy Babio, Jordi Salas-Salvadó
-
- Journal:
- Psychological Medicine / Volume 54 / Issue 3 / February 2024
- Published online by Cambridge University Press:
- 05 September 2023, pp. 620-630
-
- Article
- Export citation
-
Background
The coronavirus disease 2019 (COVID-19) has serious physiological and psychological consequences. The long-term (>12 weeks post-infection) impact of COVID-19 on mental health, specifically in older adults, is unclear. We longitudinally assessed the association of COVID-19 with depression symptomatology in community-dwelling older adults with metabolic syndrome within the framework of the PREDIMED-Plus cohort.
MethodsParticipants (n = 5486) aged 55–75 years were included in this longitudinal cohort. COVID-19 status (positive/negative) determined by tests (e.g. polymerase chain reaction severe acute respiratory syndrome coronavirus 2, IgG) was confirmed via event adjudication (410 cases). Pre- and post-COVID-19 depressive symptomatology was ascertained from annual assessments conducted using a validated 21-item Spanish Beck Depression Inventory-II (BDI-II). Multivariable linear and logistic regression models assessed the association between COVID-19 and depression symptomatology.
ResultsCOVID-19 in older adults was associated with higher post-COVID-19 BDI-II scores measured at a median (interquartile range) of 29 (15–40) weeks post-infection [fully adjusted β = 0.65 points, 95% confidence interval (CI) 0.15–1.15; p = 0.011]. This association was particularly prominent in women (β = 1.38 points, 95% CI 0.44–2.33, p = 0.004). COVID-19 was associated with 62% increased odds of elevated depression risk (BDI-II ≥ 14) post-COVID-19 when adjusted for confounders (odds ratio; 95% CI 1.13–2.30, p = 0.008).
ConclusionsCOVID-19 was associated with long-term depression risk in older adults with overweight/obesity and metabolic syndrome, particularly in women. Thus, long-term evaluations of the impact of COVID-19 on mental health and preventive public health initiatives are warranted in older adults.
Chemical and Ultrastructural Features of the Lichen-volcanic/Sedimentary Rock Interface in a Semiarid Region (Almería, Spain)
- Virginia Souza-Egipsy, Jacek Wierzchos, Jose Vicente García-Ramos, Carmen Ascaso
-
- Journal:
- The Lichenologist / Volume 34 / Issue 2 / March 2002
- Published online by Cambridge University Press:
- 28 March 2007, pp. 155-167
- Print publication:
- March 2002
-
- Article
- Export citation
-
The chemical and ultrastructural features of the interface formed by different biotypes of saxicolous lichen species with their rock substrata were investigated in the semiarid habitat of the SE Iberian Peninsula and the relationships between the bioweathering patterns observed and lichen colonization selectivity towards the different rock substrata evaluated. Xanthoria parietina was able to fix to the rock substratum by the adherence of single cell walls from the lower cortex. Neofuscelia pulla used rhizines and loose groups of hyphae for attachment of the thallus to the rock. Colonization by the foliose lichen species was confined to the rock surface, while Diploschistes diacapsis was also able grow below the surface showing two types of hyphal growth. Minerals in close contact with cell walls were biochemically and biophysically weathered, but hyphae showing calcium oxalate crystals did not appear to be directly involved in the patterns observed. The textural characteristics of the substratum seemed to be related to the type of microorganism colonization: sedimentary rocks were more deeply colonized by lichens and other chasmolithic microorganisms than volcanic material. Calcium oxalate crystals were found in the medulla of N. pulla but not at the lichen-substratum interface. Crustose lichens such as D. diacapsis showed calcium oxalate crystals in the upper cortex and over the outside of fungal medullary hyphae but not in direct contact with the rock surface. Calcium oxalate precipitation seems to be related to the different metabolic activities of the mycobiont within the lichen thallus and to different species. D. diacapsis inhibits the growth of other microorganisms in close proximity to the thallus, whereas foliose species were associated with several communities of microorganisms.